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2017


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Improving performance of linear field generation with multi-coil setup by optimizing coils position

Aghaeifar, A., Loktyushin, A., Eschelbach, M., Scheffler, K.

Magnetic Resonance Materials in Physics, Biology and Medicine, 30(Supplement 1):S259, 34th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB), October 2017 (poster)

link (url) DOI [BibTex]

2017

link (url) DOI [BibTex]


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Estimating B0 inhomogeneities with projection FID navigator readouts

Loktyushin, A., Ehses, P., Schölkopf, B., Scheffler, K.

25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), April 2017 (poster)

link (url) [BibTex]

link (url) [BibTex]


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Image Quality Improvement by Applying Retrospective Motion Correction on Quantitative Susceptibility Mapping and R2*

Feng, X., Loktyushin, A., Deistung, A., Reichenbach, J.

25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), April 2017 (poster)

link (url) [BibTex]

link (url) [BibTex]


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Generalized phase locking analysis of electrophysiology data

Safavi, S., Panagiotaropoulos, T., Kapoor, V., Logothetis, N. K., Besserve, M.

ESI Systems Neuroscience Conference (ESI-SyNC 2017): Principles of Structural and Functional Connectivity, 2017 (poster)

[BibTex]

[BibTex]

2009


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Learning Probabilistic Models via Bayesian Inverse Planning

Boularias, A., Chaib-Draa, B.

NIPS Workshop on Probabilistic Approaches for Robotics and Control, December 2009 (poster)

PDF Web [BibTex]

2009

PDF Web [BibTex]


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Bayesian Quadratic Reinforcement Learning

Hennig, P., Stern, D., Graepel, T.

NIPS Workshop on Probabilistic Approaches for Robotics and Control, December 2009 (poster)

PDF Web [BibTex]

PDF Web [BibTex]


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Policy Transfer in Apprenticeship Learning

Boularias, A., Chaib-Draa, B.

NIPS Workshop on Transfer Learning for Structured Data (TLSD-09), December 2009 (poster)

PDF Web [BibTex]

PDF Web [BibTex]


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Clinical PET/MRI-System and Its Applications with MRI Based Attenuation Correction

Kolb, A., Hofmann, M., Sossi, V., Wehrl, H., Sauter, A., Schmid, A., Schlemmer, H., Claussen, C., Pichler, B.

IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC 2009), 2009, pages: 1, October 2009 (poster)

Abstract
Clinical PET/MRI is an emerging new hybrid imaging modality. In addition to provide an unique possibility for multifunctional imaging with temporally and spatially matched data, it also provides anatomical information that can also be used for attenuation correction with no radiation exposure to the subjects. A plus of combined compared to sequential PET and MR imaging is the reduction of total scan time. Here we present our initial experience with a hybrid brain PET/MRI system. Due to the ethical approval patient scans could only be performed after a diagnostic PET/CT. We estimate that in approximately 50% of the cases PET/MRI was of superior diagnostic value compared to PET/CT and was able to provide additional information, such as DTI, spectroscopy and Time Of Flight (TOF) angiography. Here we present 3 patient cases in oncology, a retropharyngeal carcinoma in neurooncology, a relapsing meningioma and in neurology a pharyngeal carcinoma in addition to an infraction of the right hemisphere. For quantitative PET imaging attenuation correction is obligatory. In current PET/MRI setup we used our MRI based atlas method for calculating the mu-map for attenuation correction. MR-based attenuation correction accuracy was quantitatively compared to CT-based PET attenuation correction. Extensive studies to assess potential mutual interferences between PET and MR imaging modalities as well as NEMA measurements have been performed. The first patient studies as well as the phantom tests clearly demonstrated the overall good imaging performance of this first human PET/MRI system. Ongoing work concentrates on advanced normalization and reconstruction methods incorporating count-rate based algorithms.

Web [BibTex]

Web [BibTex]


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A flowering-time gene network model for association analysis in Arabidopsis thaliana

Klotzbücher, K., Kobayashi, Y., Shervashidze, N., Borgwardt, K., Weigel, D.

2009(39):95-96, German Conference on Bioinformatics (GCB '09), September 2009 (poster)

Abstract
In our project we want to determine a set of single nucleotide polymorphisms (SNPs), which have a major effect on the flowering time of Arabidopsis thaliana. Instead of performing a genome-wide association study on all SNPs in the genome of Arabidopsis thaliana, we examine the subset of SNPs from the flowering-time gene network model. We are interested in how the results of the association study vary when using only the ascertained subset of SNPs from the flowering network model, and when additionally using the information encoded by the structure of the network model. The network model is compiled from the literature by manual analysis and contains genes which have been found to affect the flowering time of Arabidopsis thaliana [Far+08; KW07]. The genes in this model are annotated with the SNPs that are located in these genes, or in near proximity to them. In a baseline comparison between the subset of SNPs from the graph and the set of all SNPs, we omit the structural information and calculate the correlation between the individual SNPs and the flowering time phenotype by use of statistical methods. Through this we can determine the subset of SNPs with the highest correlation to the flowering time. In order to further refine this subset, we include the additional information provided by the network structure by conducting a graph-based feature pre-selection. In the further course of this project we want to validate and examine the resulting set of SNPs and their corresponding genes with experimental methods.

PDF Web [BibTex]

PDF Web [BibTex]


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Initial Data from a first PET/MRI-System and its Applications in Clinical Studies Using MRI Based Attenuation Correction

Kolb, A., Hofmann, M., Sossi, V., Wehrl, H., Sauter, A., Schmid, A., Judenhofer, M., Schlemmer, H., Claussen, C., Pichler, B.

2009 World Molecular Imaging Congress, 2009, pages: 1200, September 2009 (poster)

Web [BibTex]

Web [BibTex]


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A High-Speed Object Tracker from Off-the-Shelf Components

Lampert, C., Peters, J.

First IEEE Workshop on Computer Vision for Humanoid Robots in Real Environments at ICCV 2009, 1, pages: 1, September 2009 (poster)

Abstract
We introduce RTblob, an open-source real-time vision system for 3D object detection that achieves over 200 Hz tracking speed with only off-the-shelf hardware component. It allows fast and accurate tracking of colored objects in 3D without expensive and often custom-built hardware, instead making use of the PC graphics cards for the necessary image processing operations.

PDF Web [BibTex]

PDF Web [BibTex]


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Estimating Critical Stimulus Features from Psychophysical Data: The Decision-Image Technique Applied to Human Faces

Macke, J., Wichmann, F.

Journal of Vision, 9(8):31, 9th Annual Meeting of the Vision Sciences Society (VSS), August 2009 (poster)

Abstract
One of the main challenges in the sensory sciences is to identify the stimulus features on which the sensory systems base their computations: they are a pre-requisite for computational models of perception. We describe a technique---decision-images--- for extracting critical stimulus features based on logistic regression. Rather than embedding the stimuli in noise, as is done in classification image analysis, we want to infer the important features directly from physically heterogeneous stimuli. A Decision-image not only defines the critical region-of-interest within a stimulus but is a quantitative template which defines a direction in stimulus space. Decision-images thus enable the development of predictive models, as well as the generation of optimized stimuli for subsequent psychophysical investigations. Here we describe our method and apply it to data from a human face discrimination experiment. We show that decision-images are able to predict human responses not only in terms of overall percent correct but are able to predict, for individual observers, the probabilities with which individual faces are (mis-) classified. We then test the predictions of the models using optimized stimuli. Finally, we discuss possible generalizations of the approach and its relationships with other models.

Web DOI [BibTex]

Web DOI [BibTex]


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Semi-supervised Analysis of Human fMRI Data

Shelton, JA., Blaschko, MB., Lampert, CH., Bartels, A.

Berlin Brain Computer Interface Workshop on Advances in Neurotechnology, 2009, pages: 1, July 2009 (poster)

Abstract
Kernel Canonical Correlation Analysis (KCCA) is a general technique for subspace learning that incorporates principal components analysis (PCA) and Fisher linear discriminant analysis (LDA) as special cases. By finding directions that maximize correlation, CCA learns representations tied more closely to underlying process generating the the data and can ignore high-variance noise directions. However, for data where acquisition in a given modality is expensive or otherwise limited, CCA may suffer from small sample effects. We propose to use semisupervised Laplacian regularization to utilize data that are present in only one modality. This approach is able to find highly correlated directions that also lie along the data manifold, resulting in a more robust estimate of correlated subspaces. Functional magnetic resonance imaging (fMRI) acquired data are naturally amenable to subspace techniques as data are well aligned. fMRI data of the human brain are a particularly interesting candidate. In this study we implemented various supervised and semi-supervised versions of CCA on human fMRI data, with regression to single and multivariate labels (corresponding to video content subjects viewed during the image acquisition). In each variate condition, the semi-supervised variants of CCA performed better than the supervised variants, including a supervised variant with Laplacian regularization. We additionally analyze the weights learned by the regression in order to infer brain regions that are important to different types of visual processing.

PDF Web [BibTex]

PDF Web [BibTex]


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Optimization of k-Space Trajectories by Bayesian Experimental Design

Seeger, M., Nickisch, H., Pohmann, R., Schölkopf, B.

17(2627), 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM), April 2009 (poster)

Abstract
MR image reconstruction from undersampled k-space can be improved by nonlinear denoising estimators since they incorporate statistical prior knowledge about image sparsity. Reconstruction quality depends crucially on the undersampling design (k-space trajectory), in a manner complicated by the nonlinear and signal-dependent characteristics of these methods. We propose an algorithm to assess and optimize k-space trajectories for sparse MRI reconstruction, based on Bayesian experimental design, which is scaled up to full MR images by a novel variational relaxation to iteratively reweighted FFT or gridding computations. Designs are built sequentially by adding phase encodes predicted to be most informative, given the combination of previous measurements with image prior information.

PDF Web [BibTex]

PDF Web [BibTex]


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MR-Based Attenuation Correction for PET/MR

Hofmann, M., Steinke, F., Bezrukov, I., Kolb, A., Aschoff, P., Lichy, M., Erb, M., Nägele, T., Brady, M., Schölkopf, B., Pichler, B.

17(260), 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM), April 2009 (poster)

Abstract
There has recently been a growing interest in combining PET and MR. Attenuation correction (AC), which accounts for radiation attenuation properties of the tissue, is mandatory for quantitative PET. In the case of PET/MR the attenuation map needs to be determined from the MR image. This is intrinsically difficult as MR intensities are not related to the electron density information of the attenuation map. Using ultra-short echo (UTE) acquisition, atlas registration and machine learning, we present methods that allow prediction of the attenuation map based on the MR image both for brain and whole body imaging.

PDF Web [BibTex]

PDF Web [BibTex]

2007


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MR-Based PET Attenuation Correction: Method and Validation

Hofmann, M., Steinke, F., Scheel, V., Charpiat, G., Brady, M., Schölkopf, B., Pichler, B.

2007 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS-MIC 2007), 2007(M16-6):1-2, November 2007 (poster)

Abstract
PET/MR combines the high soft tissue contrast of Magnetic Resonance Imaging (MRI) and the functional information of Positron Emission Tomography (PET). For quantitative PET information, correction of tissue photon attenuation is mandatory. Usually in conventional PET, the attenuation map is obtained from a transmission scan, which uses a rotating source, or from the CT scan in case of combined PET/CT. In the case of a PET/MR scanner, there is insufficient space for the rotating source and ideally one would want to calculate the attenuation map from the MR image instead. Since MR images provide information about proton density of the different tissue types, it is not trivial to use this data for PET attenuation correction. We present a method for predicting the PET attenuation map from a given the MR image, using a combination of atlas-registration and recognition of local patterns. Using "leave one out cross validation" we show on a database of 16 MR-CT image pairs that our method reliably allows estimating the CT image from the MR image. Subsequently, as in PET/CT, the PET attenuation map can be predicted from the CT image. On an additional dataset of MR/CT/PET triplets we quantitatively validate that our approach allows PET quantification with an error that is smaller than what would be clinically significant. We demonstrate our approach on T1-weighted human brain scans. However, the presented methods are more general and current research focuses on applying the established methods to human whole body PET/MRI applications.

PDF PDF [BibTex]

2007

PDF PDF [BibTex]


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Estimating receptive fields without spike-triggering

Macke, J., Zeck, G., Bethge, M.

37th annual Meeting of the Society for Neuroscience (Neuroscience 2007), 37(768.1):1, November 2007 (poster)

Web [BibTex]

Web [BibTex]


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Evaluation of Deformable Registration Methods for MR-CT Atlas Alignment

Scheel, V., Hofmann, M., Rehfeld, N., Judenhofer, M., Claussen, C., Pichler, B.

2007 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS-MIC 2007), 2007(M13-121):1, November 2007 (poster)

Abstract
Deformable registration methods are essential for multimodality imaging. Many different methods exist but due to the complexity of the deformed images a direct comparison of the methods is difficult. One particular application that requires high accuracy registration of MR-CT images is atlas-based attenuation correction for PET/MR. We compare four deformable registration algorithms for 3D image data included in the Open Source "National Library of Medicine Insight Segmentation and Registration Toolkit" (ITK). An interactive landmark based registration using MiraView (Siemens) has been used as gold standard. The automatic algorithms provided by ITK are based on the metrics Mattes mutual information as well as on normalized mutual information. The transformations are calculated by interpolating over a uniform B-Spline grid laying over the image to be warped. The algorithms were tested on head images from 10 subjects. We implemented a measure which segments head interior bone and air based on the CT images and l ow intensity classes of corresponding MRI images. The segmentation of bone is performed by individually calculating the lowest Hounsfield unit threshold for each CT image. The compromise is made by quantifying the number of overlapping voxels of the remaining structures. We show that the algorithms provided by ITK achieve similar or better accuracy than the time-consuming interactive landmark based registration. Thus, ITK provides an ideal platform to generate accurately fused datasets from different modalities, required for example for building training datasets for Atlas-based attenuation correction.

PDF [BibTex]

PDF [BibTex]


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A time/frequency decomposition of information transmission by LFPs and spikes in the primary visual cortex

Belitski, A., Gretton, A., Magri, C., Murayama, Y., Montemurro, M., Logothetis, N., Panzeri, S.

37th Annual Meeting of the Society for Neuroscience (Neuroscience 2007), 37, pages: 1, November 2007 (poster)

Web [BibTex]

Web [BibTex]


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Mining expression-dependent modules in the human interaction network

Georgii, E., Dietmann, S., Uno, T., Pagel, P., Tsuda, K.

BMC Bioinformatics, 8(Suppl. 8):S4, November 2007 (poster)

PDF DOI [BibTex]

PDF DOI [BibTex]


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A Hilbert Space Embedding for Distributions

Smola, A., Gretton, A., Song, L., Schölkopf, B.

Proceedings of the 10th International Conference on Discovery Science (DS 2007), 10, pages: 40-41, October 2007 (poster)

Abstract
While kernel methods are the basis of many popular techniques in supervised learning, they are less commonly used in testing, estimation, and analysis of probability distributions, where information theoretic approaches rule the roost. However it becomes difficult to estimate mutual information or entropy if the data are high dimensional.

PDF PDF DOI [BibTex]

PDF PDF DOI [BibTex]


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Studying the effects of noise correlations on population coding using a sampling method

Ecker, A., Berens, P., Bethge, M., Logothetis, N., Tolias, A.

Neural Coding, Computation and Dynamics (NCCD 07), 1, pages: 21, September 2007 (poster)

PDF [BibTex]

PDF [BibTex]


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Near-Maximum Entropy Models for Binary Neural Representations of Natural Images

Berens, P., Bethge, M.

Neural Coding, Computation and Dynamics (NCCD 07), 1, pages: 19, September 2007 (poster)

Abstract
Maximum entropy analysis of binary variables provides an elegant way for studying the role of pairwise correlations in neural populations. Unfortunately, these approaches suffer from their poor scalability to high dimensions. In sensory coding, however, high-dimensional data is ubiquitous. Here, we introduce a new approach using a near-maximum entropy model, that makes this type of analysis feasible for very high-dimensional data---the model parameters can be derived in closed form and sampling is easy. We demonstrate its usefulness by studying a simple neural representation model of natural images. For the first time, we are able to directly compare predictions from a pairwise maximum entropy model not only in small groups of neurons, but also in larger populations of more than thousand units. Our results indicate that in such larger networks interactions exist that are not predicted by pairwise correlations, despite the fact that pairwise correlations explain the lower-dimensional marginal statistics extrem ely well up to the limit of dimensionality where estimation of the full joint distribution is feasible.

PDF [BibTex]

PDF [BibTex]


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Learning the Influence of Spatio-Temporal Variations in Local Image Structure on Visual Saliency

Kienzle, W., Wichmann, F., Schölkopf, B., Franz, M.

10th T{\"u}binger Wahrnehmungskonferenz (TWK 2007), 10, pages: 1, July 2007 (poster)

Abstract
Computational models for bottom-up visual attention traditionally consist of a bank of Gabor-like or Difference-of-Gaussians filters and a nonlinear combination scheme which combines the filter responses into a real-valued saliency measure [1]. Recently it was shown that a standard machine learning algorithm can be used to derive a saliency model from human eye movement data with a very small number of additional assumptions. The learned model is much simpler than previous models, but nevertheless has state-of-the-art prediction performance [2]. A central result from this study is that DoG-like center-surround filters emerge as the unique solution to optimizing the predictivity of the model. Here we extend the learning method to the temporal domain. While the previous model [2] predicts visual saliency based on local pixel intensities in a static image, our model also takes into account temporal intensity variations. We find that the learned model responds strongly to temporal intensity changes ocurring 200-250ms before a saccade is initiated. This delay coincides with the typical saccadic latencies, indicating that the learning algorithm has extracted a meaningful statistic from the training data. In addition, we show that the model correctly predicts a significant proportion of human eye movements on previously unseen test data.

Web [BibTex]

Web [BibTex]


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Better Codes for the P300 Visual Speller

Biessmann, F., Hill, N., Farquhar, J., Schölkopf, B.

G{\"o}ttingen Meeting of the German Neuroscience Society, 7, pages: 123, March 2007 (poster)

PDF [BibTex]

PDF [BibTex]


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Do We Know What the Early Visual System Computes?

Bethge, M., Kayser, C.

31st G{\"o}ttingen Neurobiology Conference, 31, pages: 352, March 2007 (poster)

Abstract
Decades of research provided much data and insights into the mechanisms of the early visual system. Currently, however, there is great controversy on whether these findings can provide us with a thorough functional understanding of what the early visual system does, or formulated differently, of what it computes. At the Society for Neuroscience meeting 2005 in Washington, a symposium was held on the question "Do we know that the early visual system does", which was accompanied by a widely regarded publication in the Journal of Neuroscience. Yet, that discussion was rather specialized as it predominantly addressed the question of how well neural responses in retina, LGN, and cortex can be predicted from noise stimuli, but did not emphasize the question of whether we understand what the function of these early visual areas is. Here we will concentrate on this neuro-computational aspect of vision. Experts from neurobiology, psychophysics and computational neuroscience will present studies which approach this question from different viewpoints and promote a critical discussion of whether we actually understand what early areas contribute to the processing and perception of visual information.

PDF [BibTex]

PDF [BibTex]


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Implicit Wiener Series for Estimating Nonlinear Receptive Fields

Franz, MO., Macke, JH., Saleem, A., Schultz, SR.

31st G{\"o}ttingen Neurobiology Conference, 31, pages: 1199, March 2007 (poster)

PDF [BibTex]

PDF [BibTex]


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3D Reconstruction of Neural Circuits from Serial EM Images

Maack, N., Kapfer, C., Macke, J., Schölkopf, B., Denk, W., Borst, A.

31st G{\"o}ttingen Neurobiology Conference, 31, pages: 1195, March 2007 (poster)

PDF [BibTex]

PDF [BibTex]


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Identifying temporal population codes in the retina using canonical correlation analysis

Bethge, M., Macke, J., Gerwinn, S., Zeck, G.

31st G{\"o}ttingen Neurobiology Conference, 31, pages: 359, March 2007 (poster)

PDF PDF [BibTex]

PDF PDF [BibTex]


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Bayesian Neural System identification: error bars, receptive fields and neural couplings

Gerwinn, S., Seeger, M., Zeck, G., Bethge, M.

31st G{\"o}ttingen Neurobiology Conference, 31, pages: 360, March 2007 (poster)

PDF PDF [BibTex]

PDF PDF [BibTex]


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About the Triangle Inequality in Perceptual Spaces

Jäkel, F., Schölkopf, B., Wichmann, F.

Proceedings of the Computational and Systems Neuroscience Meeting 2007 (COSYNE), 4, pages: 308, February 2007 (poster)

PDF Web [BibTex]

PDF Web [BibTex]


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Center-surround filters emerge from optimizing predictivity in a free-viewing task

Kienzle, W., Wichmann, F., Schölkopf, B., Franz, M.

Proceedings of the Computational and Systems Neuroscience Meeting 2007 (COSYNE), 4, pages: 207, February 2007 (poster)

PDF Web [BibTex]

PDF Web [BibTex]


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Nonlinear Receptive Field Analysis: Making Kernel Methods Interpretable

Kienzle, W., Macke, J., Wichmann, F., Schölkopf, B., Franz, M.

Computational and Systems Neuroscience Meeting 2007 (COSYNE 2007), 4, pages: 16, February 2007 (poster)

PDF Web [BibTex]

PDF Web [BibTex]


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Estimating Population Receptive Fields in Space and Time

Macke, J., Zeck, G., Bethge, M.

Computational and Systems Neuroscience Meeting 2007 (COSYNE 2007), 4, pages: 44, February 2007 (poster)

PDF Web [BibTex]

PDF Web [BibTex]

2002


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Real-Time Statistical Learning for Oculomotor Control and Visuomotor Coordination

Vijayakumar, S., Souza, A., Peters, J., Conradt, J., Rutkowski, T., Ijspeert, A., Nakanishi, J., Inoue, M., Shibata, T., Wiryo, A., Itti, L., Amari, S., Schaal, S.

(Editors: Becker, S. , S. Thrun, K. Obermayer), Sixteenth Annual Conference on Neural Information Processing Systems (NIPS), December 2002 (poster)

Web [BibTex]

2002

Web [BibTex]


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Surface-slant-from-texture discrimination: Effects of slant level and texture type

Rosas, P., Wichmann, F., Wagemans, J.

Journal of Vision, 2(7):300, Second Annual Meeting of the Vision Sciences Society (VSS), November 2002 (poster)

Abstract
The problem of surface-slant-from-texture was studied psychophysically by measuring the performances of five human subjects in a slant-discrimination task with a number of different types of textures: uniform lattices, randomly displaced lattices, polka dots, Voronoi tessellations, orthogonal sinusoidal plaid patterns, fractal or 1/f noise, “coherent” noise and a “diffusion-based” texture (leopard skin-like). The results show: (1) Improving performance with larger slants for all textures. (2) A “non-symmetrical” performance around a particular slant characterized by a psychometric function that is steeper in the direction of the more slanted orientation. (3) For sufficiently large slants (66 deg) there are no major differences in performance between any of the different textures. (4) For slants at 26, 37 and 53 degrees, however, there are marked differences between the different textures. (5) The observed differences in performance across textures for slants up to 53 degrees are systematic within subjects, and nearly so across them. This allows a rank-order of textures to be formed according to their “helpfulness” — that is, how easy the discrimination task is when a particular texture is mapped on the surface. Polka dots tended to allow the best slant discrimination performance, noise patterns the worst up to the large slant of 66 degrees at which performance was almost independent of the particular texture chosen. Finally, our large number of 2AFC trials (approximately 2800 trials per texture across subjects) and associated tight confidence intervals may enable us to find out about which statistical properties of the textures could be responsible for surface-slant-from-texture estimation, with the ultimate goal of being able to predict observer performance for any arbitrary texture.

Web DOI [BibTex]

Web DOI [BibTex]


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Modelling Contrast Transfer in Spatial Vision

Wichmann, F.

Journal of Vision, 2(10):7, Second Annual Meeting of the Vision Sciences Society (VSS), November 2002 (poster)

Abstract
Much of our information about spatial vision comes from detection experiments involving low-contrast stimuli. Contrast discrimination experiments provide one way to explore the visual system's response to stimuli of higher contrast, the results of which allow different models of contrast processing (e.g. energy versus gain-control models) to be critically assessed (Wichmann & Henning, 1999). Studies of detection and discrimination using pulse train stimuli in noise, on the other hand, make predictions about the number, position and properties of noise sources within the processing stream (Henning, Bird & Wichmann, 2002). Here I report modelling results combining data from both sinusoidal and pulse train experiments in and without noise to arrive at a more tightly constrained model of early spatial vision.

Web DOI [BibTex]

Web DOI [BibTex]


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Pulse train detection and discrimination in pink noise

Henning, G., Wichmann, F., Bird, C.

Journal of Vision, 2(7):229, Second Annual Meeting of the Vision Sciences Society (VSS), November 2002 (poster)

Abstract
Much of our information about spatial vision comes from detection experiments involving low-contrast stimuli. Contrast discrimination experiments provide one way to explore the visual system's response to stimuli of higher contrast. We explored both detection and contrast discrimination performance with sinusoidal and "pulse-train" (or line) gratings. Both types of grating had a fundamental spatial frequency of 2.09-c/deg but the pulse-train, ideally, contains, in addition to its fundamental component, all the harmonics of the fundamental. Although the 2.09-c/deg pulse-train produced on the display was measured and shown to contain at least 8 harmonics at equal contrast, it was no more detectable than its most detectable component; no benefit from having additional information at the harmonics was measurable. The addition of broadband "pink" noise, designed to equalize the detectability of the components of the pulse train, made it about a factor of four more detectable than any of its components. However, in contrast-discrimination experiments, with an in-phase pedestal or masking grating of the same form and phase as the signal and 15% contrast, the noise did not improve the discrimination performance of the pulse train relative to that of its sinusoidal components. In contrast, a 2.09-c/deg "super train," constructed to have 8 equally detectable harmonics, was a factor of five more detectable than any of its components. We discuss the implications of these observations for models of early vision in particular the implications for possible sources of internal noise.

Web DOI [BibTex]

Web DOI [BibTex]


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Phase information in the recognition of natural images

Braun, D., Wichmann, F., Gegenfurtner, K.

Perception, 31(ECVP Abstract Supplement):133, 25th European Conference on Visual Perception, August 2002 (poster)

Abstract
Fourier phase plays an important role in determining global image structure. For example, when the phase spectrum of an image of a flower is swapped with that of a tank, we usually perceive a tank, even though the amplitude spectrum is still that of the flower. Similarly, when the phase spectrum of an image is randomly swapped across frequencies, that is its Fourier energy is randomly distributed over the image, the resulting image becomes impossible to recognise. Our goal was to evaluate the effect of phase manipulations in a quantitative manner. Subjects viewed two images of natural scenes, one of which contained an animal (the target) embedded in the background. The spectra of the images were manipulated by adding random phase noise at each frequency. The phase noise was the independent variable, uniformly distributed between 0° and ±180°. Subjects were remarkably resistant to phase noise. Even with ±120° noise, subjects were still 75% correct. The proportion of correct answers closely followed the correlation between original and noise-distorted images. Thus it appears as if it was not the global phase information per se that determines our percept of natural images, but rather the effect of phase on local image features.

Web [BibTex]

Web [BibTex]


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Detection and discrimination in pink noise

Wichmann, F., Henning, G.

5, pages: 100, 5. T{\"u}binger Wahrnehmungskonferenz (TWK), February 2002 (poster)

Abstract
Much of our information about early spatial vision comes from detection experiments involving low-contrast stimuli, which are not, perhaps, particularly "natural" stimuli. Contrast discrimination experiments provide one way to explore the visual system's response to stimuli of higher contrast whilst keeping the number of unknown parameters comparatively small. We explored both detection and contrast discrimination performance with sinusoidal and "pulse-train" (or line) gratings. Both types of grating had a fundamental spatial frequency of 2.09-c/deg but the pulse-train, ideally, contains, in addition to its fundamental component, all the harmonics of the fundamental. Although the 2.09-c/deg pulse-train produced on our display was measured using a high-performance digital camera (Photometrics) and shown to contain at least 8 harmonics at equal contrast, it was no more detectable than its most detectable component; no benefit from having additional information at the harmonics was measurable. The addition of broadband 1-D "pink" noise made it about a factor of four more detectable than any of its components. However, in contrast-discrimination experiments, with an in-phase pedestal or masking grating of the same form and phase as the signal and 15% contrast, the noise did not improve the discrimination performance of the pulse train relative to that of its sinusoidal components. We discuss the implications of these observations for models of early vision in particular the implications for possible sources of internal noise.

Web [BibTex]

Web [BibTex]


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Application of Monte Carlo Methods to Psychometric Function Fitting

Wichmann, F.

Proceedings of the 33rd European Conference on Mathematical Psychology, pages: 44, 2002 (poster)

Abstract
The psychometric function relates an observer's performance to an independent variable, usually some physical quantity of a stimulus in a psychophysical task. Here I describe methods to (1) fitting psychometric functions, (2) assessing goodness-of-fit, and (3) providing confidence intervals for the function's parameters and other estimates derived from them. First I describe a constrained maximum-likelihood method for parameter estimation. Using Monte-Carlo simulations I demonstrate that it is important to have a fitting method that takes stimulus-independent errors (or "lapses") into account. Second, a number of goodness-of-fit tests are introduced. Because psychophysical data sets are usually rather small I advocate the use of Monte Carlo resampling techniques that do not rely on asymptotic theory for goodness-of-fit assessment. Third, a parametric bootstrap is employed to estimate the variability of fitted parameters and derived quantities such as thresholds and slopes. I describe how the bootstrap bridging assumption, on which the validity of the procedure depends, can be tested without incurring too high a cost in computation time. Finally I describe how the methods can be extended to test hypotheses concerning the form and shape of several psychometric functions. Software describing the methods is available (http://www.bootstrap-software.com/psignifit/), as well as articles describing the methods in detail (Wichmann&Hill, Perception&Psychophysics, 2001a,b).

[BibTex]

[BibTex]


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Optimal linear estimation of self-motion - a real-world test of a model of fly tangential neurons

Franz, MO.

SAB 02 Workshop, Robotics as theoretical biology, 7th meeting of the International Society for Simulation of Adaptive Behaviour (SAB), (Editors: Prescott, T.; Webb, B.), 2002 (poster)

Abstract
The tangential neurons in the fly brain are sensitive to the typical optic flow patterns generated during self-motion (see example in Fig.1). We examine whether a simplified linear model of these neurons can be used to estimate self-motion from the optic flow. We present a theory for the construction of an optimal linear estimator incorporating prior knowledge both about the distance distribution of the environment, and about the noise and self-motion statistics of the sensor. The optimal estimator is tested on a gantry carrying an omnidirectional vision sensor that can be moved along three translational and one rotational degree of freedom. The experiments indicate that the proposed approach yields accurate results for rotation estimates, independently of the current translation and scene layout. Translation estimates, however, turned out to be sensitive to simultaneous rotation and to the particular distance distribution of the scene. The gantry experiments confirm that the receptive field organization of the tangential neurons allows them, as an ensemble, to extract self-motion from the optic flow.

PDF [BibTex]

PDF [BibTex]

1996


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Aktives Erwerben eines Ansichtsgraphen zur diskreten Repräsentation offener Umwelten.

Franz, M., Schölkopf, B., Mallot, H., Bülthoff, H.

Fortschritte der K{\"u}nstlichen Intelligenz, pages: 138-147, (Editors: M. Thielscher and S.-E. Bornscheuer), 1996 (poster)

PDF PostScript [BibTex]

1996

PDF PostScript [BibTex]


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Does motion-blur facilitate motion detection ?

Wichmann, F., Henning, G.

OSA Conference Program, pages: S127, 1996 (poster)

Abstract
Retinal-image motion induces the perceptual loss of high spatial-frequency content - motion blur - that affects broadband stimuli. The relative detectability of motion blur and motion itself, measured in 2-AFC experiments, shows that, although the blur associated with motion can be detected, motion itself is the more effective cue.

[BibTex]

[BibTex]