Publications | Empirical Inference - Max Planck Institute for Intelligent Systems

Twenty-Second Annual Computational Neuroscience Meeting (CNS*2013), July 2013, journal = {BMC Neuroscience}, year = {2013}, month = {7}, volume = {14}, number = {Supplement 1}, pages = {A1}, (talk)

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Logothetis, N., Eschenko, O., Murayama, Y., Augath, M., Steudel, T., Evrard, H., Besserve, M., Oeltermann, A. Studying large-scale brain networks: electrical stimulation and neural-event-triggered fMRI Twenty-Second Annual Computational Neuroscience Meeting (CNS*2013), July 2013, journal = {BMC Neuroscience}, year = {2013}, month = {7}, volume = {14}, number = {Supplement 1}, pages = {A1}, (talk)

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Modelling and Learning Approaches to Image Denoising

Burger, HC.

Eberhard Karls Universität Tübingen, Germany, 2013 (phdthesis)

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Burger, HC. Modelling and Learning Approaches to Image Denoising Eberhard Karls Universität Tübingen, Germany, 2013 (phdthesis)

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MR-Based Attenuation Correction for Combined Brain PET/MR: Robustness of Atlas- and Pattern Recognition Method to Atlas Registration Failures

Mantlik, F., Bezrukov, I., Hofmann, M., Schölkopf, B., Pichler, B.

IEEE Nuclear Science Symposium and Medical Imaging Conference (IEEE MIC), 2013 (talk)

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Mantlik, F., Bezrukov, I., Hofmann, M., Schölkopf, B., Pichler, B. MR-Based Attenuation Correction for Combined Brain PET/MR: Robustness of Atlas- and Pattern Recognition Method to Atlas Registration Failures IEEE Nuclear Science Symposium and Medical Imaging Conference (IEEE MIC), 2013 (talk)

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Domain Generalization via Invariant Feature Representation

Muandet, K.

30th International Conference on Machine Learning (ICML2013), 2013 (talk)

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Muandet, K. Domain Generalization via Invariant Feature Representation 30th International Conference on Machine Learning (ICML2013), 2013 (talk)

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Random Projections (Computational and Biological Learning Lab, University of Cambridge, 2013)

Lopez-Paz, D., Duvenaud, D.

2013 (talk)

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Lopez-Paz, D., Duvenaud, D. Random Projections (Computational and Biological Learning Lab, University of Cambridge, 2013) 2013 (talk)

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Linear mixed models for genome-wide association studies

Lippert, C.

University of Tübingen, Germany, 2013 (phdthesis)

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Lippert, C. Linear mixed models for genome-wide association studies University of Tübingen, Germany, 2013 (phdthesis)

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Modeling and Learning Complex Motor Tasks: A case study on Robot Table Tennis

Mülling, K.

Technical University Darmstadt, Germany, 2013 (phdthesis)

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Mülling, K. Modeling and Learning Complex Motor Tasks: A case study on Robot Table Tennis Technical University Darmstadt, Germany, 2013 (phdthesis)

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Intention Inference and Decision Making with Hierarchical Gaussian Process Dynamics Models

Wang, Z.

Technical University Darmstadt, Germany, 2013 (phdthesis)

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Wang, Z. Intention Inference and Decision Making with Hierarchical Gaussian Process Dynamics Models Technical University Darmstadt, Germany, 2013 (phdthesis)

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2009

Machine Learning for Brain-Computer Interfaces

Hill, NJ.

Mini-Symposia on Assistive Machine Learning for People with Disabilities at NIPS (AMD), December 2009 (talk)

Abstract

Brain-computer interfaces (BCI) aim to be the ultimate in assistive technology: decoding a user‘s intentions directly from brain signals without involving any muscles or peripheral nerves. Thus, some classes of BCI potentially offer hope for users with even the most extreme cases of paralysis, such as in late-stage Amyotrophic Lateral Sclerosis, where nothing else currently allows communication of any kind. Other lines in BCI research aim to restore lost motor function in as natural a way as possible, reconnecting and in some cases re-training motor-cortical areas to control prosthetic, or previously paretic, limbs. Research and development are progressing on both invasive and non-invasive fronts, although BCI has yet to make a breakthrough to widespread clinical application. The high-noise high-dimensional nature of brain-signals, particularly in non-invasive approaches and in patient populations, make robust decoding techniques a necessity. Generally, the approach has been to use relatively simple feature extraction techniques, such as template matching and band-power estimation, coupled to simple linear classifiers. This has led to a prevailing view among applied BCI researchers that (sophisticated) machine-learning is irrelevant since "it doesn‘t matter what classifier you use once you‘ve done your preprocessing right and extracted the right features." I shall show a few examples of how this runs counter to both the empirical reality and the spirit of what needs to be done to bring BCI into clinical application. Along the way I‘ll highlight some of the interesting problems that remain open for machine-learners.

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2009

Hill, NJ. Machine Learning for Brain-Computer Interfaces Mini-Symposia on Assistive Machine Learning for People with Disabilities at NIPS (AMD), December 2009 (talk)

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PAC-Bayesian Approach to Formulation of Clustering Objectives

Seldin, Y.

NIPS Workshop on "Clustering: Science or Art? Towards Principled Approaches", December 2009 (talk)

Abstract

Clustering is a widely used tool for exploratory data analysis. However, the theoretical understanding of clustering is very limited. We still do not have a well-founded answer to the seemingly simple question of "how many clusters are present in the data?", and furthermore a formal comparison of clusterings based on different optimization objectives is far beyond our abilities. The lack of good theoretical support gives rise to multiple heuristics that confuse the practitioners and stall development of the field. We suggest that the ill-posed nature of clustering problems is caused by the fact that clustering is often taken out of its subsequent application context. We argue that one does not cluster the data just for the sake of clustering it, but rather to facilitate the solution of some higher level task. By evaluation of the clustering‘s contribution to the solution of the higher level task it is possible to compare different clusterings, even those obtained by different optimization objectives. In the preceding work it was shown that such an approach can be applied to evaluation and design of co-clustering solutions. Here we suggest that this approach can be extended to other settings, where clustering is applied.

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Seldin, Y. PAC-Bayesian Approach to Formulation of Clustering Objectives NIPS Workshop on "Clustering: Science or Art? Towards Principled Approaches", December 2009 (talk)

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Semi-supervised Kernel Canonical Correlation Analysis of Human Functional Magnetic Resonance Imaging Data

Shelton, JA.

Women in Machine Learning Workshop (WiML), December 2009 (talk)

Abstract

Kernel Canonical Correlation Analysis (KCCA) is a general technique for subspace learning that incorporates principal components analysis (PCA) and Fisher linear discriminant analysis (LDA) as special cases. By finding directions that maximize correlation, KCCA learns representations tied more closely to underlying process generating the the data and can ignore high-variance noise directions. However, for data where acquisition in a given modality is expensive or otherwise limited, KCCA may suffer from small sample effects. We propose to use semi-supervised Laplacian regularization to utilize data that are present in only one modality. This manifold learning approach is able to find highly correlated directions that also lie along the data manifold, resulting in a more robust estimate of correlated subspaces. Functional magnetic resonance imaging (fMRI) acquired data are naturally amenable to subspace techniques as data are well aligned and such data of the human brain are a particularly interesting candidate. In this study we implemented various supervised and semi-supervised versions of KCCA on human fMRI data, with regression to single and multivariate labels (corresponding to video content subjects viewed during the image acquisition). In each variate condition, Laplacian regularization improved performance whereas the semi-supervised variants of KCCA yielded the best performance. We additionally analyze the weights learned by the regression in order to infer brain regions that are important during different types of visual processing.

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Shelton, JA. Semi-supervised Kernel Canonical Correlation Analysis of Human Functional Magnetic Resonance Imaging Data Women in Machine Learning Workshop (WiML), December 2009 (talk)

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Event-Related Potentials in Brain-Computer Interfacing

Hill, NJ.

Invited lecture on the bachelor & masters course "Introduction to Brain-Computer Interfacing", October 2009 (talk)

Abstract

An introduction to event-related potentials with specific reference to their use in brain-computer interfacing applications and research.

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Hill, NJ. Event-Related Potentials in Brain-Computer Interfacing Invited lecture on the bachelor & masters course "Introduction to Brain-Computer Interfacing", October 2009 (talk)

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BCI2000 and Python

Hill, NJ.

Invited lecture at the 5th International BCI2000 Workshop, October 2009 (talk)

Abstract

A tutorial, with exercises, on how to integrate your own Python code with the BCI2000 software package.

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Hill, NJ. BCI2000 and Python Invited lecture at the 5th International BCI2000 Workshop, October 2009 (talk)

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Implementing a Signal Processing Filter in BCI2000 Using C++

Hill, NJ., Mellinger, J.

Invited lecture at the 5th International BCI2000 Workshop, October 2009 (talk)

Abstract

This tutorial shows how the functionality of the BCI2000 software package can be extended with one‘s own code, using BCI2000‘s C++ API.

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Hill, NJ., Mellinger, J. Implementing a Signal Processing Filter in BCI2000 Using C++ Invited lecture at the 5th International BCI2000 Workshop, October 2009 (talk)

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Kernel Learning Approaches for Image Classification

Gehler, PV.

Biologische Kybernetik, Universität des Saarlandes, Saarbrücken, Germany, October 2009 (phdthesis)

Abstract

This thesis extends the use of kernel learning techniques to specific problems of image classification. Kernel learning is a paradigm in the field of machine learning that generalizes the use of inner products to compute similarities between arbitrary objects. In image classification one aims to separate images based on their visual content. We address two important problems that arise in this context: learning with weak label information and combination of heterogeneous data sources. The contributions we report on are not unique to image classification, and apply to a more general class of problems. We study the problem of learning with label ambiguity in the multiple instance learning framework. We discuss several different image classification scenarios that arise in this context and argue that the standard multiple instance learning requires a more detailed disambiguation. Finally we review kernel learning approaches proposed for this problem and derive a more efficient algorithm to solve them. The multiple kernel learning framework is an approach to automatically select kernel parameters. We extend it to its infinite limit and present an algorithm to solve the resulting problem. This result is then applied in two directions. We show how to learn kernels that adapt to the special structure of images. Finally we compare different ways of combining image features for object classification and present significant improvements compared to previous methods.

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Gehler, PV. Kernel Learning Approaches for Image Classification Biologische Kybernetik, Universität des Saarlandes, Saarbrücken, Germany, October 2009 (phdthesis)

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A PAC-Bayesian Approach to Structure Learning

Seldin, Y.

Biologische Kybernetik, The Hebrew University of Jerusalem, Israel, September 2009 (phdthesis)

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Seldin, Y. A PAC-Bayesian Approach to Structure Learning Biologische Kybernetik, The Hebrew University of Jerusalem, Israel, September 2009 (phdthesis)

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Randomized algorithms for statistical image analysis based on percolation theory

Davies, P., Langovoy, M., Wittich, O.

27th European Meeting of Statisticians (EMS), July 2009 (talk)

Abstract

We propose a novel probabilistic method for detection of signals and reconstruction of images in the presence of random noise. The method uses results from percolation and random graph theories (see Grimmett (1999)). We address the problem of detection and estimation of signals in situations where the signal-to-noise ratio is particularly low. We present an algorithm that allows to detect objects of various shapes in noisy images. The algorithm has linear complexity and exponential accuracy. Our algorithm substantially diers from wavelets-based algorithms (see Arias-Castro et.al. (2005)). Moreover, we present an algorithm that produces a crude estimate of an object based on the noisy picture. This algorithm also has linear complexity and is appropriate for real-time systems. We prove results on consistency and algorithmic complexity of our procedures.

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Davies, P., Langovoy, M., Wittich, O. Randomized algorithms for statistical image analysis based on percolation theory 27th European Meeting of Statisticians (EMS), July 2009 (talk)

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Learning Motor Primitives for Robotics

Kober, J., Peters, J., Oztop, E.

Advanced Telecommunications Research Center ATR, June 2009 (talk)

Abstract

The acquisition and self-improvement of novel motor skills is among the most important problems in robotics. Motor primitives offer one of the most promising frameworks for the application of machine learning techniques in this context. Employing the Dynamic Systems Motor primitives originally introduced by Ijspeert et al. (2003), appropriate learning algorithms for a concerted approach of both imitation and reinforcement learning are presented. Using these algorithms new motor skills, i.e., Ball-in-a-Cup, Ball-Paddling and Dart-Throwing, are learned.

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Kober, J., Peters, J., Oztop, E. Learning Motor Primitives for Robotics Advanced Telecommunications Research Center ATR, June 2009 (talk)

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Learning To Detect Unseen Object Classes by Between-Class Attribute Transfer

Lampert, C.

IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR), June 2009 (talk)

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Lampert, C. Learning To Detect Unseen Object Classes by Between-Class Attribute Transfer IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR), June 2009 (talk)

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Kernel Methods in Computer Vision:Object Localization, Clustering,and Taxonomy Discovery

Blaschko, MB.

Biologische Kybernetik, Technische Universität Berlin, Berlin, Germany, March 2009 (phdthesis)

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Blaschko, MB. Kernel Methods in Computer Vision:Object Localization, Clustering,and Taxonomy Discovery Biologische Kybernetik, Technische Universität Berlin, Berlin, Germany, March 2009 (phdthesis)

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Motor Control and Learning in Table Tennis

Mülling, K.

Eberhard Karls Universität Tübingen, Gerrmany, 2009 (diplomathesis)

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Mülling, K. Motor Control and Learning in Table Tennis Eberhard Karls Universität Tübingen, Gerrmany, 2009 (diplomathesis)

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Hierarchical Clustering and Density Estimation Based on k-nearest-neighbor graphs

Drewe, P.

Eberhard Karls Universität Tübingen, Germany, 2009 (diplomathesis)

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Drewe, P. Hierarchical Clustering and Density Estimation Based on k-nearest-neighbor graphs Eberhard Karls Universität Tübingen, Germany, 2009 (diplomathesis)

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Learning with Structured Data: Applications to Computer Vision

Nowozin, S.

Technische Universität Berlin, Germany, 2009 (phdthesis)

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Nowozin, S. Learning with Structured Data: Applications to Computer Vision Technische Universität Berlin, Germany, 2009 (phdthesis)

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From Differential Equations to Differential Geometry: Aspects of Regularisation in Machine Learning

Steinke, F.

Universität des Saarlandes, Saarbrücken, Germany, 2009 (phdthesis)

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Steinke, F. From Differential Equations to Differential Geometry: Aspects of Regularisation in Machine Learning Universität des Saarlandes, Saarbrücken, Germany, 2009 (phdthesis)

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2006

A Kernel Method for the Two-Sample-Problem

Gretton, A., Borgwardt, K., Rasch, M., Schölkopf, B., Smola, A.

20th Annual Conference on Neural Information Processing Systems (NIPS), December 2006 (talk)

Abstract

We propose two statistical tests to determine if two samples are from different distributions. Our test statistic is in both cases the distance between the means of the two samples mapped into a reproducing kernel Hilbert space (RKHS). The first test is based on a large deviation bound for the test statistic, while the second is based on the asymptotic distribution of this statistic. We show that the test statistic can be computed in $O(m^2)$ time. We apply our approach to a variety of problems, including attribute matching for databases using the Hungarian marriage method, where our test performs strongly. We also demonstrate excellent performance when comparing distributions over graphs, for which no alternative tests currently exist.

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2006

Gretton, A., Borgwardt, K., Rasch, M., Schölkopf, B., Smola, A. A Kernel Method for the Two-Sample-Problem 20th Annual Conference on Neural Information Processing Systems (NIPS), December 2006 (talk)

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Ab-initio gene finding using machine learning

Schweikert, G., Zeller, G., Zien, A., Ong, C., de Bona, F., Sonnenburg, S., Phillips, P., Rätsch, G.

NIPS Workshop on New Problems and Methods in Computational Biology, December 2006 (talk)

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Schweikert, G., Zeller, G., Zien, A., Ong, C., de Bona, F., Sonnenburg, S., Phillips, P., Rätsch, G. Ab-initio gene finding using machine learning NIPS Workshop on New Problems and Methods in Computational Biology, December 2006 (talk)

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Reinforcement Learning by Reward-Weighted Regression

Peters, J.

NIPS Workshop: Towards a New Reinforcement Learning? , December 2006 (talk)

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Peters, J. Reinforcement Learning by Reward-Weighted Regression NIPS Workshop: Towards a New Reinforcement Learning? , December 2006 (talk)

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Graph boosting for molecular QSAR analysis

Saigo, H., Kadowaki, T., Kudo, T., Tsuda, K.

NIPS Workshop on New Problems and Methods in Computational Biology, December 2006 (talk)

Abstract

We propose a new boosting method that systematically combines graph mining and mathematical programming-based machine learning. Informative and interpretable subgraph features are greedily found by a series of graph mining calls. Due to our mathematical programming formulation, subgraph features and pre-calculated real-valued features are seemlessly integrated. We tested our algorithm on a quantitative structure-activity relationship (QSAR) problem, which is basically a regression problem when given a set of chemical compounds. In benchmark experiments, the prediction accuracy of our method favorably compared with the best results reported on each dataset.

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Saigo, H., Kadowaki, T., Kudo, T., Tsuda, K. Graph boosting for molecular QSAR analysis NIPS Workshop on New Problems and Methods in Computational Biology, December 2006 (talk)

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Inferring Causal Directions by Evaluating the Complexity of Conditional Distributions

Sun, X., Janzing, D., Schölkopf, B.

NIPS Workshop on Causality and Feature Selection, December 2006 (talk)

Abstract

We propose a new approach to infer the causal structure that has generated the observed statistical dependences among n random variables. The idea is that the factorization of the joint measure of cause and effect into P(cause)P(effect|cause) leads typically to simpler conditionals than non-causal factorizations. To evaluate the complexity of the conditionals we have tried two methods. First, we have compared them to those which maximize the conditional entropy subject to the observed first and second moments since we consider the latter as the simplest conditionals. Second, we have fitted the data with conditional probability measures being exponents of functions in an RKHS space and defined the complexity by a Hilbert-space semi-norm. Such a complexity measure has several properties that are useful for our purpose. We describe some encouraging results with both methods applied to real-world data. Moreover, we have combined constraint-based approaches to causal discovery (i.e., methods using only information on conditional statistical dependences) with our method in order to distinguish between causal hypotheses which are equivalent with respect to the imposed independences. Furthermore, we compare the performance to Bayesian approaches to causal inference.

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Sun, X., Janzing, D., Schölkopf, B. Inferring Causal Directions by Evaluating the Complexity of Conditional Distributions NIPS Workshop on Causality and Feature Selection, December 2006 (talk)

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Learning Optimal EEG Features Across Time, Frequency and Space

Farquhar, J., Hill, J., Schölkopf, B.

NIPS Workshop on Current Trends in Brain-Computer Interfacing, December 2006 (talk)

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Farquhar, J., Hill, J., Schölkopf, B. Learning Optimal EEG Features Across Time, Frequency and Space NIPS Workshop on Current Trends in Brain-Computer Interfacing, December 2006 (talk)

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Semi-Supervised Learning

Zien, A.

Advanced Methods in Sequence Analysis Lectures, November 2006 (talk)

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Zien, A. Semi-Supervised Learning Advanced Methods in Sequence Analysis Lectures, November 2006 (talk)

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A Machine Learning Approach for Determining the PET Attenuation Map from Magnetic Resonance Images

Hofmann, M., Steinke, F., Judenhofer, M., Claussen, C., Schölkopf, B., Pichler, B.

IEEE Medical Imaging Conference, November 2006 (talk)

Abstract

A promising new combination in multimodality imaging is MR-PET, where the high soft tissue contrast of Magnetic Resonance Imaging (MRI) and the functional information of Positron Emission Tomography (PET) are combined. Although many technical problems have recently been solved, it is still an open problem to determine the attenuation map from the available MR scan, as the MR intensities are not directly related to the attenuation values. One standard approach is an atlas registration where the atlas MR image is aligned with the patient MR thus also yielding an attenuation image for the patient. We also propose another approach, which to our knowledge has not been tried before: Using Support Vector Machines we predict the attenuation value directly from the local image information. We train this well-established machine learning algorithm using small image patches. Although both approaches sometimes yielded acceptable results, they also showed their specific shortcomings: The registration often fails with large deformations whereas the prediction approach is problematic when the local image structure is not characteristic enough. However, the failures often do not coincide and integration of both information sources is promising. We therefore developed a combination method extending Support Vector Machines to use not only local image structure but also atlas registered coordinates. We demonstrate the strength of this combination approach on a number of examples.

[BibTex]

Hofmann, M., Steinke, F., Judenhofer, M., Claussen, C., Schölkopf, B., Pichler, B. A Machine Learning Approach for Determining the PET Attenuation Map from Magnetic Resonance Images IEEE Medical Imaging Conference, November 2006 (talk)

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Semi-Supervised Support Vector Machines and Application to Spam Filtering

Zien, A.

ECML Discovery Challenge Workshop, September 2006 (talk)

Abstract

After introducing the semi-supervised support vector machine (aka TSVM for "transductive SVM"), a few popular training strategies are briefly presented. Then the assumptions underlying semi-supervised learning are reviewed. Finally, two modern TSVM optimization techniques are applied to the spam filtering data sets of the workshop; it is shown that they can achieve excellent results, if the problem of the data being non-iid can be handled properly.

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Zien, A. Semi-Supervised Support Vector Machines and Application to Spam Filtering ECML Discovery Challenge Workshop, September 2006 (talk)

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Extraction of visual features from natural video data using Slow Feature Analysis

Nickisch, H.

Biologische Kybernetik, Technische Universität Berlin, Berlin, Germany, September 2006 (diplomathesis)

Abstract

Das Forschungsprojekt NeuRoBot hat das un{\"u}berwachte Erlernen einer neuronal inspirierten Steuerungsarchitektur zum Ziel, und zwar unter den Randbedingungen biologischer Plausibilit{\"a}t und der Benutzung einer Kamera als einzigen Sensor. Visuelle Merkmale, die ein angemessenes Abbild der Umgebung liefern, sind unerl{\"a}sslich, um das Ziel kollisionsfreier Navigation zu erreichen. Zeitliche Koh{\"a}renz ist ein neues Lernprinzip, das in der Lage ist, Erkenntnisse aus der Biologie des Sehens zu reproduzieren. Es wird durch die Beobachtung motiviert, dass die Sensoren der Retina auf deutlich k{\"u}rzeren Zeitskalen variieren als eine abstrakte Beschreibung. Zeitliche Langsamkeitsanalyse l{\"o}st das Problem, indem sie zeitlich langsam ver{\"a}nderliche Signale aus schnell ver{\"a}nderlichen Eingabesignalen extrahiert. Eine Verallgemeinerung auf Signale, die nichtlinear von den Eingaben abh{\"a}ngen, ist durch die Anwendung des Kernel-Tricks m{\"o}glich. Das einzig benutzte Vorwissen ist die zeitliche Glattheit der gewonnenen Signale. In der vorliegenden Diplomarbeit wird Langsamkeitsanalyse auf Bildausschnitte von Videos einer Roboterkamera und einer Simulationsumgebung angewendet. Zuallererst werden mittels Parameterexploration und Kreuzvalidierung die langsamst m{\"o}glichen Funktionen bestimmt. Anschließend werden die Merkmalsfunktionen analysiert und einige Ansatzpunkte f{\"u}r ihre Interpretation angegeben. Aufgrund der sehr großen Datens{\"a}tze und der umfangreichen Berechnungen behandelt ein Großteil dieser Arbeit auch Aufwandsbetrachtungen und Fragen der effizienten Berechnung. Kantendetektoren in verschiedenen Phasen und mit haupts{\"a}chlich horizontaler Orientierung stellen die wichtigsten aus der Analyse hervorgehenden Funktionen dar. Eine Anwendung auf konkrete Navigationsaufgaben des Roboters konnte bisher nicht erreicht werden. Eine visuelle Interpretation der erlernten Merkmale ist jedoch durchaus gegeben.

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Nickisch, H. Extraction of visual features from natural video data using Slow Feature Analysis Biologische Kybernetik, Technische Universität Berlin, Berlin, Germany, September 2006 (diplomathesis)

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Inferential Structure Determination: Probabilistic determination and validation of NMR structures

Habeck, M.

Gordon Research Conference on Computational Aspects of Biomolecular NMR, September 2006 (talk)

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Habeck, M. Inferential Structure Determination: Probabilistic determination and validation of NMR structures Gordon Research Conference on Computational Aspects of Biomolecular NMR, September 2006 (talk)

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An Online-Computation Approach to Optimal Finite-Horizon State-Feedback Control of Nonlinear Stochastic Systems

Deisenroth, MP.

Biologische Kybernetik, Universität Karlsruhe (TH), Karlsruhe, Germany, August 2006 (diplomathesis)

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Deisenroth, MP. An Online-Computation Approach to Optimal Finite-Horizon State-Feedback Control of Nonlinear Stochastic Systems Biologische Kybernetik, Universität Karlsruhe (TH), Karlsruhe, Germany, August 2006 (diplomathesis)

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Machine Learning Algorithms for Polymorphism Detection

Schweikert, G., Zeller, G., Clark, R., Ossowski, S., Warthmann, N., Shinn, P., Frazer, K., Ecker, J., Huson, D., Weigel, D., Schölkopf, B., Rätsch, G.

2nd ISCB Student Council Symposium, August 2006 (talk)

Abstract

Analyzing resequencing array data using machine learning, we obtain a genome-wide inventory of polymorphisms in 20 wild strains of Arabidopsis thaliana, including 750,000 single nucleotide poly- morphisms (SNPs) and thousands of highly polymorphic regions and deletions. We thus provide an unprecedented resource for the study of natural variation in plants.

Web [BibTex]

Schweikert, G., Zeller, G., Clark, R., Ossowski, S., Warthmann, N., Shinn, P., Frazer, K., Ecker, J., Huson, D., Weigel, D., Schölkopf, B., Rätsch, G. Machine Learning Algorithms for Polymorphism Detection 2nd ISCB Student Council Symposium, August 2006 (talk)

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Inferential structure determination: Overview and new developments

Habeck, M.

Sixth CCPN Annual Conference: Efficient and Rapid Structure Determination by NMR, July 2006 (talk)

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Habeck, M. Inferential structure determination: Overview and new developments Sixth CCPN Annual Conference: Efficient and Rapid Structure Determination by NMR, July 2006 (talk)

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MCMC inference in (Conditionally) Conjugate Dirichlet Process Gaussian Mixture Models

Rasmussen, C., Görür, D.

ICML Workshop on Learning with Nonparametric Bayesian Methods, June 2006 (talk)

Abstract

We compare the predictive accuracy of the Dirichlet Process Gaussian mixture models using conjugate and conditionally conjugate priors and show that better density models result from using the wider class of priors. We explore several MCMC schemes exploiting conditional conjugacy and show their computational merits on several multidimensional density estimation problems.

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Rasmussen, C., Görür, D. MCMC inference in (Conditionally) Conjugate Dirichlet Process Gaussian Mixture Models ICML Workshop on Learning with Nonparametric Bayesian Methods, June 2006 (talk)

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