Publications | Empirical Inference - Max Planck Institute for Intelligent Systems

30 results (View BibTeX file of all listed publications)

2009

Machine Learning for Brain-Computer Interfaces

Hill, NJ.

Mini-Symposia on Assistive Machine Learning for People with Disabilities at NIPS (AMD), December 2009 (talk)

Abstract

Brain-computer interfaces (BCI) aim to be the ultimate in assistive technology: decoding a user‘s intentions directly from brain signals without involving any muscles or peripheral nerves. Thus, some classes of BCI potentially offer hope for users with even the most extreme cases of paralysis, such as in late-stage Amyotrophic Lateral Sclerosis, where nothing else currently allows communication of any kind. Other lines in BCI research aim to restore lost motor function in as natural a way as possible, reconnecting and in some cases re-training motor-cortical areas to control prosthetic, or previously paretic, limbs. Research and development are progressing on both invasive and non-invasive fronts, although BCI has yet to make a breakthrough to widespread clinical application. The high-noise high-dimensional nature of brain-signals, particularly in non-invasive approaches and in patient populations, make robust decoding techniques a necessity. Generally, the approach has been to use relatively simple feature extraction techniques, such as template matching and band-power estimation, coupled to simple linear classifiers. This has led to a prevailing view among applied BCI researchers that (sophisticated) machine-learning is irrelevant since "it doesn‘t matter what classifier you use once you‘ve done your preprocessing right and extracted the right features." I shall show a few examples of how this runs counter to both the empirical reality and the spirit of what needs to be done to bring BCI into clinical application. Along the way I‘ll highlight some of the interesting problems that remain open for machine-learners.

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2009

Hill, NJ. Machine Learning for Brain-Computer Interfaces Mini-Symposia on Assistive Machine Learning for People with Disabilities at NIPS (AMD), December 2009 (talk)

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PAC-Bayesian Approach to Formulation of Clustering Objectives

Seldin, Y.

NIPS Workshop on "Clustering: Science or Art? Towards Principled Approaches", December 2009 (talk)

Abstract

Clustering is a widely used tool for exploratory data analysis. However, the theoretical understanding of clustering is very limited. We still do not have a well-founded answer to the seemingly simple question of "how many clusters are present in the data?", and furthermore a formal comparison of clusterings based on different optimization objectives is far beyond our abilities. The lack of good theoretical support gives rise to multiple heuristics that confuse the practitioners and stall development of the field. We suggest that the ill-posed nature of clustering problems is caused by the fact that clustering is often taken out of its subsequent application context. We argue that one does not cluster the data just for the sake of clustering it, but rather to facilitate the solution of some higher level task. By evaluation of the clustering‘s contribution to the solution of the higher level task it is possible to compare different clusterings, even those obtained by different optimization objectives. In the preceding work it was shown that such an approach can be applied to evaluation and design of co-clustering solutions. Here we suggest that this approach can be extended to other settings, where clustering is applied.

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Seldin, Y. PAC-Bayesian Approach to Formulation of Clustering Objectives NIPS Workshop on "Clustering: Science or Art? Towards Principled Approaches", December 2009 (talk)

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Semi-supervised Kernel Canonical Correlation Analysis of Human Functional Magnetic Resonance Imaging Data

Shelton, JA.

Women in Machine Learning Workshop (WiML), December 2009 (talk)

Abstract

Kernel Canonical Correlation Analysis (KCCA) is a general technique for subspace learning that incorporates principal components analysis (PCA) and Fisher linear discriminant analysis (LDA) as special cases. By finding directions that maximize correlation, KCCA learns representations tied more closely to underlying process generating the the data and can ignore high-variance noise directions. However, for data where acquisition in a given modality is expensive or otherwise limited, KCCA may suffer from small sample effects. We propose to use semi-supervised Laplacian regularization to utilize data that are present in only one modality. This manifold learning approach is able to find highly correlated directions that also lie along the data manifold, resulting in a more robust estimate of correlated subspaces. Functional magnetic resonance imaging (fMRI) acquired data are naturally amenable to subspace techniques as data are well aligned and such data of the human brain are a particularly interesting candidate. In this study we implemented various supervised and semi-supervised versions of KCCA on human fMRI data, with regression to single and multivariate labels (corresponding to video content subjects viewed during the image acquisition). In each variate condition, Laplacian regularization improved performance whereas the semi-supervised variants of KCCA yielded the best performance. We additionally analyze the weights learned by the regression in order to infer brain regions that are important during different types of visual processing.

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