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2016


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Nonlinear functional causal models for distinguishing cause from effect

Zhang, K., Hyvärinen, A.

In Statistics and Causality: Methods for Applied Empirical Research, pages: 185-201, 8, 1st, (Editors: Wolfgang Wiedermann and Alexander von Eye), John Wiley & Sons, Inc., 2016 (inbook)

[BibTex]

2016

[BibTex]


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Analysis of multiparametric MRI using a semi-supervised random forest framework allows the detection of therapy response in ischemic stroke

Castaneda, S., Katiyar, P., Russo, F., Calaminus, C., Disselhorst, J. A., Ziemann, U., Kohlhofer, U., Quintanilla-Martinez, L., Poli, S., Pichler, B. J.

World Molecular Imaging Conference, 2016 (talk)

link (url) [BibTex]

link (url) [BibTex]


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A cognitive brain–computer interface for patients with amyotrophic lateral sclerosis

Hohmann, M., Fomina, T., Jayaram, V., Widmann, N., Förster, C., Just, J., Synofzik, M., Schölkopf, B., Schöls, L., Grosse-Wentrup, M.

In Brain-Computer Interfaces: Lab Experiments to Real-World Applications, 228(Supplement C):221-239, 8, Progress in Brain Research, (Editors: Damien Coyle), Elsevier, 2016 (incollection)

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Multi-view learning on multiparametric PET/MRI quantifies intratumoral heterogeneity and determines therapy efficacy

Katiyar, P., Divine, M. R., Kohlhofer, U., Quintanilla-Martinez, L., Siegemund, M., Pfizenmaier, K., Kontermann, R., Pichler, B. J., Disselhorst, J. A.

World Molecular Imaging Conference, 2016 (talk)

link (url) [BibTex]

link (url) [BibTex]

2015


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easyGWAS: An Integrated Computational Framework for Advanced Genome-Wide Association Studies

Grimm, Dominik

Eberhard Karls Universität Tübingen, November 2015 (phdthesis)

[BibTex]

2015

[BibTex]


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Causal Discovery Beyond Conditional Independences

Sgouritsa, E.

Eberhard Karls Universität Tübingen, Germany, October 2015 (phdthesis)

link (url) [BibTex]

link (url) [BibTex]


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Causal Inference for Empirical Time Series Based on the Postulate of Independence of Cause and Mechanism

Besserve, M.

53rd Annual Allerton Conference on Communication, Control, and Computing, September 2015 (talk)

[BibTex]

[BibTex]


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From Points to Probability Measures: A Statistical Learning on Distributions with Kernel Mean Embedding

Muandet, K.

University of Tübingen, Germany, University of Tübingen, Germany, September 2015 (phdthesis)

[BibTex]

[BibTex]


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Machine Learning Approaches to Image Deconvolution

Schuler, C.

University of Tübingen, Germany, University of Tübingen, Germany, September 2015 (phdthesis)

[BibTex]

[BibTex]


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Kernel methods in medical imaging

Charpiat, G., Hofmann, M., Schölkopf, B.

In Handbook of Biomedical Imaging, pages: 63-81, 4, (Editors: Paragios, N., Duncan, J. and Ayache, N.), Springer, Berlin, Germany, June 2015 (inbook)

Web link (url) [BibTex]

Web link (url) [BibTex]


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Blind Retrospective Motion Correction of MR Images

Loktyushin, A.

University of Tübingen, Germany, May 2015 (phdthesis)

[BibTex]

[BibTex]


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Independence of cause and mechanism in brain networks

Besserve, M.

DALI workshop on Networks: Processes and Causality, April 2015 (talk)

[BibTex]

[BibTex]


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Information-Theoretic Implications of Classical and Quantum Causal Structures

Chaves, R., Majenz, C., Luft, L., Maciel, T., Janzing, D., Schölkopf, B., Gross, D.

18th Conference on Quantum Information Processing (QIP), 2015 (talk)

Web link (url) [BibTex]

Web link (url) [BibTex]


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Assessment of brain tissue damage in the Sub-Acute Stroke Region by Multiparametric Imaging using [89-Zr]-Desferal-EPO-PET/MRI

Castaneda, S. G., Katiyar, P., Russo, F., Disselhorst, J. A., Calaminus, C., Poli, S., Maurer, A., Ziemann, U., Pichler, B. J.

World Molecular Imaging Conference, 2015 (talk)

[BibTex]

[BibTex]


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Statistical and Machine Learning Methods for Neuroimaging: Examples, Challenges, and Extensions to Diffusion Imaging Data

O’Donnell, L. J., Schultz, T.

In Visualization and Processing of Higher Order Descriptors for Multi-Valued Data, pages: 299-319, (Editors: Hotz, I. and Schultz, T.), Springer, 2015 (inbook)

[BibTex]

[BibTex]


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A Cognitive Brain-Computer Interface for Patients with Amyotrophic Lateral Sclerosis

Hohmann, M.

Graduate Training Centre of Neuroscience, University of Tübingen, Germany, 2015 (mastersthesis)

[BibTex]

[BibTex]


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Early time point in vivo PET/MR is a promising biomarker for determining efficacy of a novel Db(\alphaEGFR)-scTRAIL fusion protein therapy in a colon cancer model

Divine, M. R., Harant, M., Katiyar, P., Disselhorst, J. A., Bukala, D., Aidone, S., Siegemund, M., Pfizenmaier, K., Kontermann, R., Pichler, B. J.

World Molecular Imaging Conference, 2015 (talk)

[BibTex]

[BibTex]


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Sequential Image Deconvolution Using Probabilistic Linear Algebra

Gao, M.

Technical University of Munich, Germany, 2015 (mastersthesis)

[BibTex]

[BibTex]


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Causal Inference in Neuroimaging

Casarsa de Azevedo, L.

Graduate Training Centre of Neuroscience, University of Tübingen, Germany, 2015 (mastersthesis)

[BibTex]

[BibTex]


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The effect of frowning on attention

Ibarra Chaoul, A.

Graduate Training Centre of Neuroscience, University of Tübingen, Germany, 2015 (mastersthesis)

[BibTex]

[BibTex]


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Justifying Information-Geometric Causal Inference

Janzing, D., Steudel, B., Shajarisales, N., Schölkopf, B.

In Measures of Complexity: Festschrift for Alexey Chervonenkis, pages: 253-265, 18, (Editors: Vovk, V., Papadopoulos, H. and Gammerman, A.), Springer, 2015 (inbook)

DOI [BibTex]

DOI [BibTex]


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The search for single exoplanet transits in the Kepler light curves

Foreman-Mackey, D., Hogg, D. W., Schölkopf, B.

IAU General Assembly, 22, pages: 2258352, 2015 (talk)

link (url) [BibTex]

link (url) [BibTex]

2014


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Modeling the polygenic architecture of complex traits

Rakitsch, Barbara

Eberhard Karls Universität Tübingen, November 2014 (phdthesis)

[BibTex]

2014

[BibTex]


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Unsupervised identification of neural events in local field potentials

Besserve, M., Schölkopf, B., Logothetis, N. K.

44th Annual Meeting of the Society for Neuroscience (Neuroscience), 2014 (talk)

[BibTex]

[BibTex]


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A Novel Causal Inference Method for Time Series

Shajarisales, N.

Eberhard Karls Universität Tübingen, Germany, Eberhard Karls Universität Tübingen, Germany, 2014 (mastersthesis)

PDF [BibTex]

PDF [BibTex]


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Quantifying statistical dependency

Besserve, M.

Research Network on Learning Systems Summer School, 2014 (talk)

[BibTex]

[BibTex]


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Single-Source Domain Adaptation with Target and Conditional Shift

Zhang, K., Schölkopf, B., Muandet, K., Wang, Z., Zhou, Z., Persello, C.

In Regularization, Optimization, Kernels, and Support Vector Machines, pages: 427-456, 19, Chapman & Hall/CRC Machine Learning & Pattern Recognition, (Editors: Suykens, J. A. K., Signoretto, M. and Argyriou, A.), Chapman and Hall/CRC, Boca Raton, USA, 2014 (inbook)

[BibTex]

[BibTex]


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Higher-Order Tensors in Diffusion Imaging

Schultz, T., Fuster, A., Ghosh, A., Deriche, R., Florack, L., Lim, L.

In Visualization and Processing of Tensors and Higher Order Descriptors for Multi-Valued Data, pages: 129-161, Mathematics + Visualization, (Editors: Westin, C.-F., Vilanova, A. and Burgeth, B.), Springer, 2014 (inbook)

[BibTex]

[BibTex]


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Fuzzy Fibers: Uncertainty in dMRI Tractography

Schultz, T., Vilanova, A., Brecheisen, R., Kindlmann, G.

In Scientific Visualization: Uncertainty, Multifield, Biomedical, and Scalable Visualization, pages: 79-92, 8, Mathematics + Visualization, (Editors: Hansen, C. D., Chen, M., Johnson, C. R., Kaufman, A. E. and Hagen, H.), Springer, 2014 (inbook)

[BibTex]

[BibTex]


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A global analysis of extreme events and consequences for the terrestrial carbon cycle

Zscheischler, J.

Diss. No. 22043, ETH Zurich, Switzerland, ETH Zurich, Switzerland, 2014 (phdthesis)

[BibTex]

[BibTex]


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Nonconvex Proximal Splitting with Computational Errors

Sra, S.

In Regularization, Optimization, Kernels, and Support Vector Machines, pages: 83-102, 4, (Editors: Suykens, J. A. K., Signoretto, M. and Argyriou, A.), CRC Press, 2014 (inbook)

[BibTex]

[BibTex]


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Development of advanced methods for improving astronomical images

Schmeißer, N.

Eberhard Karls Universität Tübingen, Germany, Eberhard Karls Universität Tübingen, Germany, 2014 (diplomathesis)

[BibTex]

[BibTex]


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The Feasibility of Causal Discovery in Complex Systems: An Examination of Climate Change Attribution and Detection

Lacosse, E.

Graduate Training Centre of Neuroscience, University of Tübingen, Germany, Graduate Training Centre of Neuroscience, University of Tübingen, Germany, 2014 (mastersthesis)

[BibTex]

[BibTex]


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Causal Discovery in the Presence of Time-Dependent Relations or Small Sample Size

Huang, B.

Graduate Training Centre of Neuroscience, University of Tübingen, Germany, Graduate Training Centre of Neuroscience, University of Tübingen, Germany, 2014 (mastersthesis)

[BibTex]

[BibTex]


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Active Learning - Modern Learning Theory

Balcan, M., Urner, R.

In Encyclopedia of Algorithms, (Editors: Kao, M.-Y.), Springer Berlin Heidelberg, 2014 (incollection)

link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Analysis of Distance Functions in Graphs

Alamgir, M.

University of Hamburg, Germany, University of Hamburg, Germany, 2014 (phdthesis)

[BibTex]

[BibTex]

2007


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Reaction graph kernels for discovering missing enzymes in the plant secondary metabolism

Saigo, H., Hattori, M., Tsuda, K.

NIPS Workshop on Machine Learning in Computational Biology, December 2007 (talk)

Abstract
Secondary metabolic pathway in plant is important for finding druggable candidate enzymes. However, there are many enzymes whose functions are still undiscovered especially in organism-specific metabolic pathways. We propose reaction graph kernels for automatically assigning the EC numbers to unknown enzymatic reactions in a metabolic network. Experiments are carried out on KEGG/REACTION database and our method successfully predicted the first three digits of the EC number with 83% accuracy.We also exhaustively predicted missing enzymatic functions in the plant secondary metabolism pathways, and evaluated our results in biochemical validity.

Web [BibTex]

2007

Web [BibTex]


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Positional Oligomer Importance Matrices

Sonnenburg, S., Zien, A., Philips, P., Rätsch, G.

NIPS Workshop on Machine Learning in Computational Biology, December 2007 (talk)

Abstract
At the heart of many important bioinformatics problems, such as gene finding and function prediction, is the classification of biological sequences, above all of DNA and proteins. In many cases, the most accurate classifiers are obtained by training SVMs with complex sequence kernels, for instance for transcription starts or splice sites. However, an often criticized downside of SVMs with complex kernels is that it is very hard for humans to understand the learned decision rules and to derive biological insights from them. To close this gap, we introduce the concept of positional oligomer importance matrices (POIMs) and develop an efficient algorithm for their computation. We demonstrate how they overcome the limitations of sequence logos, and how they can be used to find relevant motifs for different biological phenomena in a straight-forward way. Note that the concept of POIMs is not limited to interpreting SVMs, but is applicable to general k−mer based scoring systems.

Web [BibTex]

Web [BibTex]


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Machine Learning Algorithms for Polymorphism Detection

Schweikert, G., Zeller, G., Weigel, D., Schölkopf, B., Rätsch, G.

NIPS Workshop on Machine Learning in Computational Biology, December 2007 (talk)

Web [BibTex]

Web [BibTex]


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An Automated Combination of Kernels for Predicting Protein Subcellular Localization

Zien, A., Ong, C.

NIPS Workshop on Machine Learning in Computational Biology, December 2007 (talk)

Abstract
Protein subcellular localization is a crucial ingredient to many important inferences about cellular processes, including prediction of protein function and protein interactions.We propose a new class of protein sequence kernels which considers all motifs including motifs with gaps. This class of kernels allows the inclusion of pairwise amino acid distances into their computation. We utilize an extension of the multiclass support vector machine (SVM)method which directly solves protein subcellular localization without resorting to the common approach of splitting the problem into several binary classification problems. To automatically search over families of possible amino acid motifs, we optimize over multiple kernels at the same time. We compare our automated approach to four other predictors on three different datasets, and show that we perform better than the current state of the art. Furthermore, our method provides some insights as to which features are most useful for determining subcellular localization, which are in agreement with biological reasoning.

Web [BibTex]

Web [BibTex]


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Challenges in Brain-Computer Interface Development: Induction, Measurement, Decoding, Integration

Hill, NJ.

Invited keynote talk at the launch of BrainGain, the Dutch BCI research consortium, November 2007 (talk)

Abstract
I‘ll present a perspective on Brain-Computer Interface development from T{\"u}bingen. Some of the benefits promised by BCI technology lie in the near foreseeable future, and some further away. Our motivation is to make BCI technology feasible for the people who could benefit from what it has to offer soon: namely, people in the "completely locked-in" state. I‘ll mention some of the challenges of working with this user group, and explain the specific directions they have motivated us to take in developing experimental methods, algorithms, and software.

[BibTex]

[BibTex]


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Some Theoretical Aspects of Human Categorization Behavior: Similarity and Generalization

Jäkel, F.

Biologische Kybernetik, Eberhard-Karls-Universität Tübingen, Tübingen, Germany, November 2007, passed with "ausgezeichnet", summa cum laude, published online (phdthesis)

PDF [BibTex]

PDF [BibTex]


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Statistical Learning Theory Approaches to Clustering

Jegelka, S.

Biologische Kybernetik, Eberhard-Karls-Universität Tübingen, Tübingen, Germany, November 2007 (diplomathesis)

PDF [BibTex]

PDF [BibTex]


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Policy Learning for Robotics

Peters, J.

14th International Conference on Neural Information Processing (ICONIP), November 2007 (talk)

Web [BibTex]

Web [BibTex]


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Hilbert Space Representations of Probability Distributions

Gretton, A.

2nd Workshop on Machine Learning and Optimization at the ISM, October 2007 (talk)

Abstract
Many problems in unsupervised learning require the analysis of features of probability distributions. At the most fundamental level, we might wish to determine whether two distributions are the same, based on samples from each - this is known as the two-sample or homogeneity problem. We use kernel methods to address this problem, by mapping probability distributions to elements in a reproducing kernel Hilbert space (RKHS). Given a sufficiently rich RKHS, these representations are unique: thus comparing feature space representations allows us to compare distributions without ambiguity. Applications include testing whether cancer subtypes are distinguishable on the basis of DNA microarray data, and whether low frequency oscillations measured at an electrode in the cortex have a different distribution during a neural spike. A more difficult problem is to discover whether two random variables drawn from a joint distribution are independent. It turns out that any dependence between pairs of random variables can be encoded in a cross-covariance operator between appropriate RKHS representations of the variables, and we may test independence by looking at a norm of the operator. We demonstrate this independence test by establishing dependence between an English text and its French translation, as opposed to French text on the same topic but otherwise unrelated. Finally, we show that this operator norm is itself a difference in feature means.

PDF Web [BibTex]

PDF Web [BibTex]